Chemistry Metabolic Manipulator Orlistat Essay

Metabolic Manipilator name: orlistatEach student will select a unique Metabolic Manipulator, from the list provided, addressing
the current Research (R), Diagnosis (D), and Policy (P). Students should include a brief
outline of the biochemical analysis method(s) used to detect/confirm or manage the treatment
regime for the condition, from the topic list provided. The Report must use the Headings (in
bold) below and address the following:
1. Overview (words 300)
Identify the commercial and/or chemical name(s), relevant class and/or structure of the
’Metabolic Manipulator’ molecule and contextualise the intracellular metabolic
biochemical pathways it affects (i.e. Protein, Carbohydrate, Lipid &/or Oxidative
Phosphorylation). Briefly outline the effect(s) the Manipulator has on the organism
locally (i.e. specific cells or tissue) and/or as a whole (i.e. the whole organism). Identify
the Substrates/Precursors and the biochemical/chemical synthesis steps altered or
disrupted by the Manipulator (i.e. parent and/or active molecule, key enzymes & cofactors involved in the disorder) and describe the relevant transport, half-life, receptor
activation and fate following action – Manipulator degradation within the cell/organism.
2. Research (words 200)
Describe the most recent research (published scientific article(s)) effort pertaining to the
Manipulator. This may include, but not limited to, characterization of metabolic status,
biochemical pathways, receptors and signal transduction within cells or tissue and the
identification of potential therapeutic(s) or the Manipulator as as a therapeutic agent.
3. Diagnosis (words 200)
Identify the disease state(s) produced by/or consequence(s) of treatment with the
Manipulator that arise if there is a genetic defect or chemical perturbation in the
metabolic/biosynthetic pathway of target cells/tissues.
4. Policy (word 100)
Outline the current and/or relevant policies/legislation (federal, state or international)
pertinent to the Manipulator (e.g. adverse health outcomes or legislation for
therapeutic use).
Report Format: Diagrams, graphics/illustrations maybe used (with Harvard
references). The report should be in 12pt font,
Please also provide the links for source of information.
Please use reliable sources for information
Metabolic Manipilator name: orlistat
Each student will select a unique Metabolic Manipulator, from the list provided, addressing
the current Research (R), Diagnosis (D), and Policy (P). Students should include a brief
outline of the biochemical analysis method(s) used to detect/confirm or manage the treatment
regime for the condition, from the topic list provided. The Report must use the Headings (in
bold) below and address the following:
1. Overview (words 300)
Identify the commercial and/or chemical name(s), relevant class and/or structure of the
’Metabolic Manipulator’ molecule and contextualise the intracellular metabolic
biochemical pathways it affects (i.e. Protein, Carbohydrate, Lipid &/or Oxidative
Phosphorylation). Briefly outline the effect(s) the Manipulator has on the organism
locally (i.e. specific cells or tissue) and/or as a whole (i.e. the whole organism). Identify
the Substrates/Precursors and the biochemical/chemical synthesis steps altered or
disrupted by the Manipulator (i.e. parent and/or active molecule, key enzymes & cofactors involved in the disorder) and describe the relevant transport, half-life, receptor
activation and fate following action – Manipulator degradation within the cell/organism.
2. Research (words 200)
Describe the most recent research (published scientific article(s)) effort pertaining to the
Manipulator. This may include, but not limited to, characterization of metabolic status,
biochemical pathways, receptors and signal transduction within cells or tissue and the
identification of potential therapeutic(s) or the Manipulator as as a therapeutic agent.
Please also provide the links for source of information.
Please use reliable sources for information












Bordetella pertussis pathogenesis: current and future challenges (nih.gov)
Azithromycin Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing –
WebMD
Whooping cough in Australia (13nov2018 edition)(AIHW)
Bordetella pertussis | Microbiology Spectrum (asm.org)
Department of Health | Pertussis CDNA National Guidelines for Public Health
Units
Management of Whooping Cough (Pertussis) (nsw.gov.au)
CDC Releases Guidelines on Antimicrobial Agents for the Treatment and
Postexposure Prophylaxis of Pertussis – Practice Guidelines – American Family
Physician (aafp.org)
Whooping Cough Vaccination | Pertussis | CDC
Effects of Azithromycin on Pulmonary Exacerbations in Pediatric Cystic Fibrosis Pulmonology Advisor
What are different azithromycin quantities for different bacterial infections? Health Value
virulence factors of Bordetella pertussis: a matter of control | FEMS Microbiology
Reviews | Oxford Academic (oup.com)
Pertussis (museumofhealthcare.ca) (bacteria pic)
2021, Australian Institute of Health and Welfare, viewed September 22 2021,
.
(2021)
“Azithromycin Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD” 2021,
viewed September 22 2021, .
(“Azithromycin Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD”
2021)
“Department of Health | PertussisCDNA National Guidelines for Public Health Units” 2021,
viewed September 23 2021,
.
(“Department of Health | PertussisCDNA National Guidelines for Public Health Units” 2021)

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