# Biostats; mean, median EXCEL

Directions: This take-home assignment is open-book. This means that you can use your notes, textbook, and materials on th
website found at http://blackboard.udmercy.edu/. The Excel data file can be found in the Assignments section of Blackboar
to perform the calculations requested to answer the questions below.
* Exams will be turned in on Wednesday, October 19, 2022.
* The axes of graphs need to be properly labeled.
* Answer the short essay questions by inserting textboxes into your Excel worksheets.
Path: Insert → Text → TextBox
* Upload your Excel file into the Take-home 2 digital drop box. Do not worry if the derived Blackboard PDF is not formatte
Formatting issues will be resolved when the instructor downloads the Excel file onto his computer.
Note on cheating and plagiarism: You may not get ANY help from ANYONE other than the instructor. If you have technical p
contact the instructor. The penalty for cheating on this exam is a grade of zero (0). You must digitally sign the Honor state
it in with the exam.
Honor statement: By signing this page, I affirm that I completed this open-book, open-notes take-home exam witho
help from other people (with the exception of the instructor, Dr. Stokes Baker).
Date –>
otes, textbook, and materials on the course’s
Assignments section of Blackboard. Use Excel
d Blackboard PDF is not formatted correctly.
instructor. If you have technical problems
ust digitally sign the Honor statement and hand
n-notes take-home exam without
Atherosclerosis
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Healthy
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91
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108
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81
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Q1: (2 points) What were the means and median systolic blood pressure of the
healthy and diseased population? Is there a difference between the two
populations?
Q2: (10 points) Create a relative frequency polygon that displays the distribution of each
population on the same graph. How do the distributions of each population compare?
Which method is better at comparing two populations? Use intervals of 5 mm Hg in your
graph. Describe the distribution of the class. (Number of modes, shape, skewed,
there a difference in the distributions of the two populations?
Q3: (18 points) At the research hospital you are doing your residency in, the attending
physician asked you to do a meta-analysis of the hospital records to see if using systolic
blood pressure would be a good diagnostic screen for detecting atherosclerosis.
Instructions will be posted on the Bio2900 Knowledge website.
a) Create a receiver operating characteristic curve.
b) Does the curve indicate that systolic blood pressure can be used as a diagnostic screen?
c) If so, what blood pressure should be used as an indicator of atherosclerosis concern?
(Hint: The first stage of treatment is putting your patient on a low-fat, low sodium diet.)
d) What would be that test’s sensitivity? What would be the specificity?
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essure of the
he distribution of each
population compare?
vals of 5 mm Hg in your
shape, skewed, etc.). Is
cy in, the attending
o see if using systolic
herosclerosis.
as a diagnostic screen?
erosclerosis concern?
fat, low sodium diet.)
False positive has high consequence
False positive has low consequence
(A) line of zero discrimination (AUC=0.5); (B) typical
clinical test (AUC=0.5–1.0); perfect test (AUC=1.0).
Abdul Ghaaliq Lalkhen, and Anthony McCluskey Contin Educ Anaesth Crit Care Pain 2008;8:221-223
Excel Equations
Video at https://youtu.be/-rfzhtLOYq8
Calculating Receiving Operating
Calculating Receiving Operating
Calculating Receiving Operating
What would be the appropriate sensitivity and false
positive rate?
Sensitivity: 0.943
False positive: 0.187
What would be the appropriate BMI cut-off value?
Sensitivity: 0.943
False positive: 0.187

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