Statistics Question

In Clinical Trials

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Hypothesis tests are often used in clinical trials to determine whether some new treatment, drug, procedure, etc. causes improved outcomes in patients.

  • For example, suppose a doctor believes that a new drug is able to reduce blood pressure in obese patients. To test this, he may measure the blood pressure of 40 patients before and after using the new drug for one month.
  • He then performs a hypothesis test using the following hypotheses:

    H0: ?after = ?before (the mean blood pressure is the same before and after using the drug)

    HA: ?after < ?before (the mean blood pressure is less after using the drug)

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    If the p-value of the test is less than some significance level (e.g. ? = .05), then he can reject the null hypothesis and conclude that the new drug leads to reduced blood pressure.

    In Business

  • Hypothesis tests are often used in business to determine whether or not some new advertising campaign, marketing technique, etc. causes increased sales.
  • For example, suppose a company believes that spending more money on digital advertising leads to increased sales. To test this, the company may increase money spent on digital advertising during a two-month period and collect data to see if overall sales have increased.

  • They may perform a hypothesis test using the following hypotheses:
  • H0: ?after = ?before (the mean sales is the same before and after spending more on advertising)

    HA: ?after > ?before (the mean sales increased after spending more on advertising)

    If the p-value of the test is less than some significance level (e.g. ? = .05), then the company can reject the null hypothesis and conclude that increased digital advertising leads to increased sales.

  • In Manufacturing
  • Hypothesis tests are also used often in manufacturing plants to determine if some new process, technique, method, etc. causes a change in the number of defective products produced.

    For example, suppose a certain manufacturing plant wants to test whether or not some new method changes the number of defective widgets produced per month, which is currently 250. To test this, they may measure the mean number of defective widgets produced before and after using the new method for one month.

    They can then perform a hypothesis test using the following hypotheses:

    H0: ?after = ?before (the mean number of defective widgets is the same before and after using the new method)

    HA: ?after ? ?before (the mean number of defective widgets produced is different before and after using the new method)

  • If the p-value of the test is less than some significance level (e.g. ? = .05), then the plant can reject the null hypothesis and conclude that the new method leads to a change in the number of defective widgets produced per month.
  • In classrooms

  • A principal at a certain school claims that the students in his school are above average intelligence. A random sample Links to an external site.of thirty students IQ scores have a meanLinks to an external site.score of 112.5. Is there sufficient evidence to support the principal’s claim? The mean population IQ is 100 with a standard deviatioLinks to an external site. of 15.
  • Step 1: State the

    Null hypothesiLinks to an external site.

    . The accepted fact is that the

    population meaninks to an external site.

    is 100, so: H0: ? = 100.

    Step 2: State the

    Alternate HypothesiLinks to an external site.

    . The claim is that the students have above average IQ scores, so:H1: ? > 100.The fact that we are looking for scores “greater than” a certain point means that this is a

    one-tailed test.inks to an external site.

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